Medication Disposal

person placing medications in dropboxThe Costa Mesa Sanitary District no longer has a drop box for disposing of non-controlled medications. 

Timely disposal of prescription medicine can reduce the risk of others taking the medication accidentally or misusing the medication intentionally. The best and most environmentally friendly way to dispose of your prescription medicine is through a proper drug disposal program. We have created a list of various locations that accept medication disposals in Costa Mesa and within a local radius. Commonly accepted medication waste includes prescription medications, ointments, lotions, liquid medication bottles, vitamins, aerosol cans, and inhalers.

Note: Please contact the drop off location to verify whether they accept the medications you wish to dispose of.

CVS Pharmacy Walgreens In-Store Pharmacy
3911 S Bristol St, Costa Mesa
(714) 556-7183		 1726 Superior Ave, Costa Mesa
(949) 629-9714		 VONS Pharmacy
3650 South Bristol St, Santa Ana
(714) 540-0393
1150 Baker St, Costa Mesa
(714) 662-7517		 3000 S Bristol St, Santa Ana
(714) 427-3986		  
2701 Harbor Blvd, Costa Mesa
(714) 438-1110		    
2521 Eastbluff Dr, Newport Beach
(949) 717-6642		    
5385 Alton Pkwy, Irvine
(949) 733-8226		    


Visit Orange County Waste & Recycling's website to view the various drop box locations throughout the county.

How else can I dispose of my medications?

  • All medications, including controlled substances, will be accepted at various Orange County drop sites during National Prescription Drug Take-Back Days in April and October of each year. For details and locations, visit the event website or check with your local police department.
  • Put unwanted or expired medications in a zip bag. Pour hot water into the bag. Add kitty litter, soil, or tissue paper to soak up the liquid. Place the entire bag into the mixed waste trash cart. For step-by-step instructions, click HERE.